Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mapk3  mitogen-activated protein kinase 3   (Synonyms: Erk1, Erk-1, Esrk1, Mtap2k, p44erk1, p44mapk, p44 MAP kinase, Prkm3)
Results	Reference
1	J:333984 Altes G, Vaquero M, Cuesta S, Anerillas C, Macia A, Espinet C, Ribera J, Bellusci S, Klein OD, Yeramian A, Dolcet X, Egea J, Encinas M, A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes. Cell Mol Life Sci. 2022 Sep 13;79(10):514
1	J:214083 Boucherat O, Nadeau V, Berube-Simard FA, Charron J, Jeannotte L, Crucial requirement of ERK/MAPK signaling in respiratory tract development. Development. 2014 Aug;141(16):3197-211
1	J:232617 Chen Z, Yue SX, Zhou G, Greenfield EM, Murakami S, ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation. J Bone Miner Res. 2015 May;30(5):765-74
1	J:154797 Cho KW, Cai J, Kim HY, Hosoya A, Ohshima H, Choi KY, Jung HS, ERK activation is involved in tooth development via FGF10 signaling. J Exp Zool B Mol Dev Evol. 2009 Dec 15;312(8):901-11
1*	J:131397 Cho KW, Cho SW, Lee JM, Lee MJ, Gang HS, Jung HS, Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development. Gene Expr Patterns. 2008 Apr;8(4):284-290
1	J:209617 Ehrman LA, Nardini D, Ehrman S, Rizvi TA, Gulick J, Krenz M, Dasgupta B, Robbins J, Ratner N, Nakafuku M, Waclaw RR, The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon. J Neurosci. 2014 Mar 5;34(10):3767-78
1	J:159106 Faedo A, Borello U, Rubenstein JL, Repression of fgf signaling by sprouty1-2 regulates cortical patterning in two distinct regions and times. J Neurosci. 2010 Mar 17;30(11):4015-23
1*	J:243203 Farmer DT, Finley JK, Chen FY, Tarifeno-Saldivia E, McNamara NA, Knox SM, McManus MT, miR-205 is a critical regulator of lacrimal gland development. Dev Biol. 2017 Jul 01;427(1):12-20
1	J:305202 Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hogler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C, Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028
1	J:334093 Hasan MR, Koskenranta A, Alakurtti K, Takatalo M, Rice DP, RAB23 regulates musculoskeletal development and patterning. Front Cell Dev Biol. 2023;11:1049131
1*	J:233611 Hirata A, Katayama K, Tsuji T, Imura H, Natsume N, Sugahara T, Kunieda T, Nakamura H, Otsuki Y, Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9
1	J:298585 Huang JY, Krebs BB, Miskus ML, Russell ML, Duffy EP, Graf JM, Lu HC, Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality. Sci Rep. 2020 Oct 28;10(1):18508
1	J:321519 Kelam N, Racetin A, Katsuyama Y, Vukojevic K, Kostic S, Immunohistochemical Expression Pattern of FGFR1, FGFR2, RIP5, and HIP2 in Developing and Postnatal Kidneys of Dab1(-/-) (yotari) Mice. Int J Mol Sci. 2022 Feb 11;23(4)
1	J:347411 Kimura E, Mongan M, Xiao B, Christianto A, Wang J, Carreira VS, Bolon B, Zhang X, Burns KA, Biesiada J, Medvedovic M, Puga A, Xia Y, MAP3K1 regulates female reproductive tract development. Dis Model Mech. 2024 Mar 1;17(3)
1	J:242320 Kosfeld A, Brand F, Weiss AC, Kreuzer M, Goerk M, Martens H, Schubert S, Schafer AK, Riehmer V, Hennies I, Brasen JH, Pape L, Amann K, Krogvold L, Bjerre A, Daniel C, Kispert A, Haffner D, Weber RG, Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations. Hum Mol Genet. 2017 May 01;26(9):1716-1731
1	J:91329 Kuorilehto T, Nissinen M, Koivunen J, Benson MD, Peltonen J, NF1 tumor suppressor protein and mRNA in skeletal tissues of developing and adult normal mouse and NF1-deficient embryos. J Bone Miner Res. 2004 Jun;19(6):983-9
1	J:181400 Kuracha MR, Burgess D, Siefker E, Cooper JT, Licht JD, Robinson ML, Govindarajan V, Spry1 and Spry2 are necessary for lens vesicle separation and corneal differentiation. Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6887-97
1	J:206947 Li S, Mattar P, Dixit R, Lawn SO, Wilkinson G, Kinch C, Eisenstat D, Kurrasch DM, Chan JA, Schuurmans C, RAS/ERK signaling controls proneural genetic programs in cortical development and gliomagenesis. J Neurosci. 2014 Feb 5;34(6):2169-90
1	J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19
1	J:326547 Lu P, Wang P, Wu B, Wang Y, Liu Y, Cheng W, Feng X, Yuan X, Atteya MM, Ferro H, Sugi Y, Rydquist G, Esmaily M, Butcher JT, Chang CP, Lenz J, Zheng D, Zhou B, A SOX17-PDGFB signaling axis regulates aortic root development. Nat Commun. 2022 Jul 13;13(1):4065
1	J:189960 Madakashira BP, Kobrinski DA, Hancher AD, Arneman EC, Wagner BD, Wang F, Shin H, Lovicu FJ, Reneker LW, Robinson ML, Frs2alpha enhances fibroblast growth factor-mediated survival and differentiation in lens development. Development. 2012 Dec;139(24):4601-12
1	J:216505 Meng Q, Mongan M, Wang J, Tang X, Zhang J, Kao W, Xia Y, Epithelial sheet movement requires the cooperation of c-Jun and MAP3K1. Dev Biol. 2014 Nov 1;395(1):29-37
1	J:312376 Pastar V, Lozic M, Kelam N, Filipovic N, Bernard B, Katsuyama Y, Vukojevic K, Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice. Int J Mol Sci. 2021 Oct 2;22(19)
1*	J:125029 Pelosi M, Marampon F, Zani BM, Prudente S, Perlas E, Caputo V, Cianetti L, Berno V, Narumiya S, Kang SW, Musaro A, Rosenthal N, ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program. Mol Cell Biol. 2007 Sep;27(17):6163-76
1	J:325077 Pitirri MK, Durham EL, Romano NA, Santos JI, Coupe AP, Zheng H, Chen DZ, Kawasaki K, Jabs EW, Richtsmeier JT, Wu M, Motch Perrine SM, Meckel's Cartilage in Mandibular Development and Dysmorphogenesis. Front Genet. 2022;13:871927
1	J:170365 Sanchis A, Bayo P, Sevilla LM, Perez P, Glucocorticoid receptor antagonizes EGFR function to regulate eyelid development. Int J Dev Biol. 2010;54(10):1473-80
1	J:301269 Sankoda N, Tanabe W, Tanaka A, Shibata H, Woltjen K, Chiba T, Haga H, Sakai Y, Mandai M, Yamamoto T, Yamada Y, Uemoto S, Kawaguchi Y, Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021 Jan 25;12(1):560
1	J:195711 Shi F, Fan Y, Zhang L, Meng L, Zhi H, Hu H, Lin A, The expression of Pax6 variants is subject to posttranscriptional regulation in the developing mouse eyelid. PLoS One. 2013;8(1):e53919
1	J:217449 Stanco A, Pla R, Vogt D, Chen Y, Mandal S, Walker J, Hunt RF, Lindtner S, Erdman CA, Pieper AA, Hamilton SP, Xu D, Baraban SC, Rubenstein JL, NPAS1 represses the generation of specific subtypes of cortical interneurons. Neuron. 2014 Dec 3;84(5):940-53
1	J:308676 Talley MJ, Nardini D, Qin S, Prada CE, Ehrman LA, Waclaw RR, A role for sustained MAPK activity in the mouse ventral telencephalon. Dev Biol. 2021 Aug;476:137-147
1	J:295894 Wei G, Gao N, Chen J, Fan L, Zeng Z, Gao G, Li L, Fang G, Hu K, Pang X, Fan HY, Clevers H, Liu M, Zhang X, Li D, Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation. Development. 2020 Sep 2;147(17):dev185678
1	J:339611 Yadav PS, Papaioannou G, Kobelski MM, Demay MB, Phosphate-induced activation of VEGFR2 leads to caspase-9-mediated apoptosis of hypertrophic chondrocytes. iScience. 2023 Sep 15;26(9):107548
1	J:320420 Yamaguchi H, Kitami M, Uchima Koecklin KH, He L, Wang J, Lagor WR, Perrien DS, Komatsu Y, Temporospatial regulation of intraflagellar transport is required for the endochondral ossification in mice. Dev Biol. 2022 Feb;482:91-100
1*	J:137275 Yu Z, Bhandari A, Mannik J, Pham T, Xu X, Andersen B, Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure. Dev Biol. 2008 Jul 1;319(1):56-67